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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bfd9e4e387215933ce879b061973fccdac9828b9ddc2dedfdcbee3a8b5bbb0' 
  AND token = '5zDK3Jri7uWrJcuxtNdLUDOKq1rUUGmvhndm3yuFchg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}