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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26026e6138b15fb8236f0dc2c616f26de7a0af50db8f6f6a4249edbbb43cafc3' 
  AND token = 'fY8FNR7liUxv8Aikhn2hsyEqj/vxQFD822Vh0j2NMo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}