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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a3d3f0538d12dcd8dcc201c6fa1de21155d4e238b7f8e64d20d34e02e1ae95' 
  AND token = '44Nl4pFguVHBJ6Gkth0qeOr9hKmyEab5B4y2QAHQ6vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}