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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595bb26a8934946ce53aa11f22db4f69218726849e45b78adb20b63432f83ae7' 
  AND token = 'jVNda3XFXguUTwwD/k/molUFr0TwT6CD/sQbTb6OMHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}