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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ba3cbd8f107d9b62d19c9db9470a05d969d10a14c2ddd91d29c2056c787845' 
  AND token = '+UF/Za5Z7WFB6ZAkMeMOBYCJOsUE4ESpi/zCtFZbkeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}