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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be1648b55a3a1b781037e10f77743a9a643fbcc8e18fc198d0d31169f0d1cf7' 
  AND token = 'euLpEwDUOpzDyfPo8uBZCANWfPV+DWkPWI+giUaSAFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}