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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c53eb29eb975df92b3996c8058dd699a6e978535eee8e9dc38f2d2fa46cf16b' 
  AND token = 'ivC17gwM8rbvw8TW9usZY8b5a/+jKVW/Bs4/31cYx30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}