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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50fd1c4ddf2b5bdb0a1f0ba31416c3341a37ca4bf2bde1af51f09cfdbadf47cd' 
  AND token = 'TpWyShTAM50JAqZMwrKJPRnmsgHgov/mwFLY34Xgb+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}