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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c2a948e85829a2832999120f6781aeceb9134ea3a0539b8f529f3b6df94bcd' 
  AND token = 'b2pAgxFsIjA+NNZxDNy4DTWz4EWjBt6l8t6OOhwUV6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}