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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21d866bad54cbc7596a32c99f1f1d70486a3957e1d647726b9961bfc942e8d4' 
  AND token = 'jo2+iCl/lG3IkgLdaafpni1aZgLimss1xXDzog2Hz4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}