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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42357c348383e5f6801a41989777b73576b747d7da430809d0fc09aa4bc8d4e8' 
  AND token = 'kP+1GQ1MjAWX+XX17gEfKEAnrEcYA0YEBLfc0JhYFTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}