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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a427c1490e466284a2ec941276a9a345f20b426b869fd596aeac76c743442e4' 
  AND token = 'Oy4JtZn8IQgL21USrXADbGgf+CgDgQns45cbwtqT90E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}