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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16eb101a499bb9bdf77db3bb3f5311414a75272a0c3d1191f2795699750160ae' 
  AND token = 'klswGzHA9Op3dbJuBbuwsN3v8nogfj/bPVfNnC5/XQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}