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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737a5f36ab13d3b2db300a7e4a68e062713ad3d47608c4f5f26b5ccd8589c64a' 
  AND token = 'ipxpGGUzMq7sqgGCze2EEk++2zYZI9z3BNiNqbY4I6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}