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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76770f4531eb614b9ea96f61e12a8613cbe89e91e4a1e76dfe1c78cee1f4b52f' 
  AND token = 'cVnX/NuiVYfj1MGJzJEXjS4vq6UUCyfrLobMnn+tqIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}