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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0401d622c92d49e602e233a06b7083b501eaf8c720368802d367b812ef1c1e' 
  AND token = 'yOL1tb6/1RZuRBuzsOMca2rOKV9Dg/q7Ktik8reSUFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}