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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10ebebf6373abfc73b8bd9e065cbe05bebcd92b580dadcd15a898c3d0721d8c' 
  AND token = 'lqXk8epxqsjtZEn47thWZchbhSG4vjEl0b9ME95NxlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}