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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b409a1a8997451185b4395206bd27f03d48cdeb64b6a4da99db7e855f5fe84eb' 
  AND token = 'UMjmLwbUM0eRJQMWY+IL5HsDlKWUifEIKoc55346I/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}