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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491367b38e03bafbe50ef3cf2ebe85a3bc87c3d17b04b90fb1f8cc46a5d3ca39' 
  AND token = 'AE/l4OoSStAlpNdJVs06ZC4cMje8CNIIXSVBeWNgFSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}