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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d9001b7739d1e954f4044bcc7b29267fc3c7ec8037895e4a9594a99b4620c07' 
  AND token = 'OT6YLq8SgBaCUFhKQy2noqVFhICH1IK9CoTMwvg0iEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}