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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc52d8664bb531b9ed973d5166f26044c25d8f347d61bb1cb647d057bc8fa423' 
  AND token = 'L7FZsDHnZF3zlXH2jydtsr2LMAZ4DPiWkp0n2Gj021U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}