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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e88c6849cb452c749dc93bb742065c047f70a4233d840ae37242922affb63e92' 
  AND token = 'MB2NRw99rH1LodawZQsCMBVMUqsapPgNlHMp8qX5qAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}