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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331cb01bf23842644ef7a44445a0280168fa2bd849e20695c1e53dc408b4ee93' 
  AND token = 'vNZq0HGfRVxD/y2fiM4WT0nQ7ezp6DlJtoiAlx6PCEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}