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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4901aa3c4acc6b42784f290b20c0344a9a3f6fa895e207bb20dec5483588246a' 
  AND token = 'FDzN3BxC3hJ16l+dFVMR4ZKmUn5XQ8VaLe7htnFCgLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}