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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb101158457e93d40410794848e4121541dffb2b1c851f732c5e23fba6206cc1' 
  AND token = 'fjmMank3m71KBPSIKlDpc55ZdXeigQ6QMHFXPwamRew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}