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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbd73ddbc0b96399a09ec1613f3d2917941e8c6eafea0722171fa4526f12b777' 
  AND token = '8CFiwa54DVvjeytJ09m+FAM4l2y6ItPId2SIfaOCm+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}