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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2af4c80c88a01533046508e4a17f1e2f1c8fe487dd229be5dd78d231a5dca5' 
  AND token = 'u6X7PPO3Odg6wS9FmYicQBpViV+pJLWUXhZThM0hV44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}