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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ec43b194451134bf1d17fcf5cd1307939a8301183c74d4ad6842c77fb99dc2' 
  AND token = 'iEmAtceTJ9eyCfP83M8mjSz7zKx0a10LULYKOZbIobM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}