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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901e7e550fb2038a1117072db8f542c03cba446deff4598a4249cf005cb40566' 
  AND token = 'MEDvu//AHKR+9xNrktXKK4LwS5DS+BNj8ltkIgZ/oB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}