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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '553734369cc354d0519ade740fedd457c8e3d8c002c9d0271c87cf9b5cb420c4' 
  AND token = 'C20zYwtncED9fdCHfo5mkF7gHKTbx4p8RpMntrqZ6Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}