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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc212dffe529da6f93e721740d55514dd489ef4f0ab8d716659b41cc3838a60f' 
  AND token = 'flAgp9s5A/RtJG+A6A5bUazUPf6AhYHg6xCeGxdJ0/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}