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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25150e187289564c13a4f7f81c0ccde39f0784943ee4dcdb1c6c5539ca1e6804' 
  AND token = 'vzLpPQG0dMJPLoJPU775TgOQpGFlKG2Qh4C6KUWslZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}