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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2381bca8fda12bd2ae20f0db990f25947c4e7107012b7090b2504ec23adad438' 
  AND token = 'UANdN175bHj2YtWOx5dGpi89IxztEi9GoKSDk5TRm0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}