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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '276bce51ee4c3768f181fd1206b9accc2f9c680de4d86251d48d5802f0e542df' 
  AND token = 'D/mpFrQf2DEW7KKe83novKAJ52ETbCrKLlGrRygU3WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}