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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18b62f68e21d1459fe012e5f64a32f93b54cd4bdbb717b4452dbae3827bd203' 
  AND token = 'kH6E5nfQdTEIJ39hwvxQT3cJzgM4HyIqCBtIZNPJr80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}