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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63246798d336363b40d7a6ef01bcb476b9687c93d53cdfbade1ec02fd53d92ac' 
  AND token = 'sY4RFkOdLRCvxciARjnMwnAzmDcyVr8Fb7rVWKD5UDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}