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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4b9c50e2d23989ebc15f080bb023086324dc0150f62b39079e1791349e0d1c' 
  AND token = 'MOwiS7WRPc32AJJ8ElPQw1kATwinogNB1Z434IWd1l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}