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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2789bb5a5b64760a77f920ca220afd4bfc9db9a4772f68124a39895e49811429' 
  AND token = 'XfYS7rlsTYPtRoKQ9mFuGOHEieaAahWSXGuQJtN3sgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}