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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848582f3438b1d614140292840e80d4f519297e72456c8b368a5567a4ac607b2' 
  AND token = 'zugIi5Wpo3pu4zkMtzLcpzb5ssyTN2k8FPxcZWty5h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}