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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0289c7506dc977eca8d0b843d96ee0d621a7f0891a6ba8c699028a46debac2f9' 
  AND token = 'Q+FJC43t0R8lobla4yHVL5T7dm9hmlor+uxQ+PMVfLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}