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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea9849214da06aa189bda93a2aba96d96726b435f0af1d64c08990f82d7f012' 
  AND token = 'zPG+lspmrOBKgyFyqPTKuAifo+0rUG9LoxmkDweNhR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}