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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2a861c29b99b790705c17c702104a7a2d328ac1b047d6b6f1f5f3e612bb898' 
  AND token = 'axUKmWmy0z4/FkJOnTIafl3pXpt61PZ9e0+bHEOnVAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}