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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66220f2573418edf6c7d6092aa8ec6fe06ff1c176a99bb3ebe806a31b079044a' 
  AND token = 'x5l2SxVM6ATLCQ8/LVVxNBfR+n1ymsGBkB/XuMM3ZEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}