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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2248faaec3023970779abf5717f56ab6f83a729c5c8f4130cfaa42befe0faa15' 
  AND token = 'ZLyWHfdULocBjAlM3Bp8Of1cMh0QEPksvbOXBHjavBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}