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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df70a1916b0f71c2c221df0f4204ac3f75046d5547a22be13fb817053ae4d0b2' 
  AND token = 'trY3rCT4q//qEU2GK56ok4A9mE2TNz8l8u41FAUV2DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}