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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be84222bc369d002a36e6c2d16972a1f8a0f891659e7b84c90d52417a1f0a8f' 
  AND token = 'tckZgNvb2CM5ZRIAaFqOSHoBa2N6wGfH4H+ZvYEnwAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}