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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2424a06f0ed919b87523b541639a4219b1cb7bf14e8549cddb0968b1b9c3d9' 
  AND token = '7YfCArvGtwEgAxO0U+gF6usnSfwP2ti+577OBjYue8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}