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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e369ebffd5797c92c31f42cdcd0d017a4c653c7b1e27290bf7f43c3a4e223369' 
  AND token = 'D3NcEHiBhDuVYM4qWCTbgxQqC4ZmnDt/9MbGg4eXyx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}