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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adefc03ea6af2d4ca4da7996de08027ee825b9e85078765a25e9d4b9b8908ea' 
  AND token = 'u3XxnUhR23iqLWErkBMdzsY4KMhgThttmf+CFVW9Ock=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}