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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '915143f2be1590f078a7d6625aa76fb1a0f85e8a10354bbe8382a49b77b466e7' 
  AND token = 'y8spDkIo0qwvS2/X9Sx3zGQ6PO9r8YwPU5frNV9ipRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}